Day 1 - St. Louis, MO
St. Louis, known as the “Gateway to the West,” is sure to win you over. Take in the Gateway Arch Riverfront, highlighted by the majestic Gateway Arch, which is the largest man made monument in the U.S. There’s something for everyone at St. Louis’ many world-class, free attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. You can end your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens.

Day 2 - Alton, IL
Located along magnificent limestone bluffs, Alton is a place of historical significance. Alton housed the final debate between Abraham Lincoln and Stephen Douglas, and is also the birth place of legendary jazz musician, Miles Davis. Be sure to visit the many attractions Alton has to offer, from the Lewis and Clark State Historic Site and the Great Rivers Museum to the charming homes of the Middletown Historic District. Also, discover why Alton lays claim to the most haunted city in America.

Day 3 - Hannibal, MO
Hannibal, “America’s Hometown,” is a place where you can re-discover the adventures from Mark Twain’s era. The spirits of Tom Sawyer and Huck Finn are alive in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans filled with wonderful and special shops that are unique to Hannibal. No matter what you choose to do, you will find this town to be very accommodating.

Day 4 - Burlington, IA
The ancestral home of the Sauk Indians, Burlington resounds with the myths and memories of their past. Enjoy a tour of Historic Fort Madison, where you’ll learn about life in the first military fort built on the Upper Mississippi from costumed interpreters, or explore Historic Nauvoo, an early Mormon settlement.

Day 5 - Davenport, IA
Voted one of the Most Livable Small Cities in America, Davenport is often described by newcomers and life-long residents alike as having incredibly friendly people living in a city large enough to have plenty of things to do while still retaining a hometown feel. This vibrant city features the Legacy of John Deere, the largest agricultural exhibit in the world. Music enthusiasts will enjoy partaking in Davenport’s many music festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival, which is dedicated to native Bix Beiderbecke.

Day 6 - Dubuque, IA
A “Masterpiece on the Mississippi,” Dubuque is Iowa’s oldest city and is among the oldest settlements west of the Mississippi River. Dubuque is overflowing with things to do and see. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through a whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.  No matter what you’re interested in, Dubuque has it!

Day 7 - La Crosse, WI / Winona, MN
Step into 19th Century America in La Crosse, located on the banks of three captivating rivers. Discover the heart of the Amish Country, where transportation is provided on horse and buggy. La Crosse is also home to Riverside Park, where you’ll enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures. Winona is one of the most beautiful places in the country, nestled between the covered limestone river bluffs that rise 500 feet and the stunning mighty Mississippi River. The town was named for Princess We-Noh-Nah, daughter of Chief Wapasha (Wabasha) III. When translated, it means "first-born daughter." Today it enjoys the motto of the “Island City.” Be sure to visit all the wonders of Winona, including the Winona Country Historical Society Armory Museum, St. Stanislaus Koska Catholic Church, and the Watkins Country Heritage Museum.

Day 8 - Red Wing, MN / St. Paul, MN
Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artisans, craftspeople and artists for over 150 years. Red Wing delivers a diverse blend of arts, entertainment and activities for your pleasure. Enjoy a show at Red Wing’s historic Sheldon Performing Arts Theatre or observe the beauty of nature in one of Red Wing’s 38 parks located throughout the city. St. Paul is a thrilling place to end your adventure as Minnesota’s must see capital!  History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. St. Paul’s enchanting art galleries, world class museums, and entertaining stage performances will be sure to capture your imagination. End the day by visiting Mounds Park, where visitors are treated to a beautiful panoramic view of the city.

Adventure is around every corner when you journey through America’s Heartland on American Cruise Lines’ brand new Mississippi Riverboat, Queen of the Mississippi. Drift and dream as this grand sternwheeler carries you through an ever changing tapestry of lakes, forests, and ingenious feats of engineering. The Queen of the Mississippi will embody the spirit of traditional Mississippi River cruising and the grandeur of the riverboats of the past, while offering all the modern comforts and amenities American Cruise Lines passengers have come to expect.

• Dining service, snacks and complimentary cocktail parties.
• Entertainment aboard the ship.
• Oversized staterooms – largest in industry.
• Most with private balconies.
• Flat screen satellite TV and DVD players in all staterooms.
• Wireless internet access shipwide.
• Hairdryers in all staterooms.
• Individual climate control in all staterooms.

Category A cabin onboard the Queen of the Mississippi

• Cabin upgrades are available.
• Itinerary is subject to change.
• Fares do not include shore tours, gratuities, or port charges and fees of $250 per person.
• Please ask your Vacations To Go travel counselor for more information.

For American Cruise Lines terms and conditions, please click here.

* The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines.