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Panama Vacations

Panama, uniquely situated as a land bridge connecting North and South America, is famed for the Panama Canal that links the world's largest oceans. Many Panama tours visit the Miraflores Locks on the canal's Pacific entrance. Here, you can see millions of gallons of water transferred in mere minutes, all done by gravity.

Itineraries can also feature nocturnal wildlife cruises along the Chagres River and Gatun Lake, in search of howler monkeys, toucans and myriad reptiles; aerial tram tours through the forest canopy in Soberania National Park; and opportunities to meet the self-governing, indigenous Kuna people in the San Blas archipelago.

Book Now and Save on Panama Vacations!

  • Save with early payment discounts on select Trafalgar vacations when you book and pay in full by April 28, 2016. Prices shown reflect discounts of up to 5%. Click here for eligible departures.
  • Companion flies for free from select gateways on Alexander+Robert trips when you book and pay in full by February 29, 2016. Click here for eligible departures.
  • Save 10% to 30% off select G Adventures trips when you book by February 26, 2016. Click here for eligible departures.
  • Save $600 per couple off select Alexander+Roberts itineraries when you pay in full at the time of booking. Click here for eligible departures.
  • Single travelers save $300 per person off select Alexander+Roberts trips when you book and pay in by full. Click here for eligible departures.
  • Last minute deals! Save $300 to $2,000 per couple off select Collette tours. Click here for eligible departures.
  • Reduced rates with Ponant! Prices shown reflect discount. Click here for eligible departures.
  • Pay no single supplement on select Ponant sailings in certain cabin categories. Click here for eligible departures.
  • Save 35% to 45% off select G Adventures sailings when you book by February 29, 2016. Click here for eligible departures.
  • Save $200 per couple off the land price or save $300 per couple off the air-inclusive price of select G Adventures tours when you book by February 8, 2016. Click here for eligible departures.

The vacations below are divided into two groups. First, there is a list of trips that visit only Panama, followed by a list of multi-country itineraries that include Panama.

Trips are rated according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered. The vacations below are categorized according to the industry rating scale (budget, first class and deluxe). Click any vacation name for the itinerary, dates and prices.

Vacation Name Days Starts In Ends In Travel Style Company Quality*  
Vacations in Panama Only

Panama's Pacific Beach Resorts 3 Panama City, Panama  Panama City, Panama  Independent A+R First Class Dates and Prices
Panama City 3 Panama City, Panama  Panama City, Panama  Independent A+R First Class Dates and Prices
Gamboa 3 Panama City, Panama  Panama City, Panama  Independent A+R First Class Dates and Prices
Chiriqui Highlands 3 Panama City, Panama  Panama City, Panama  Independent A+R Deluxe Dates and Prices
Bocas del Toro 4 Panama City, Panama  Panama City, Panama  Independent A+R First Class Dates and Prices
Highlights of Panama 4 Panama City, Panama  Panama City, Panama  Independent SITA First Class Dates and Prices
5 Day Panama 5 Panama City, Panama  Panama City, Panama  Escorted Gate 1 First Class Dates and Prices
Best of Panama 6 Panama City, Panama  Panama City, Panama  Independent Globus First Class Dates and Prices
Best of Panama 6 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Best of Panama 8 Panama City, Panama  Panama City, Panama  Escorted G Adventure Budget Dates and Prices
+ View all 31 vacations in Panama only
Multi-Country Vacations that Include Panama
Costa Rica and the Panama Canal (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Lindblad Deluxe Dates and Prices
Costa Rica and the Panama Canal (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Lindblad Deluxe Dates and Prices
The Panama Canal & The Wonders of Costa Rica (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Nat Hab Deluxe Dates and Prices
The Panama Canal & The Wonders of Costa Rica (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Nat Hab Deluxe Dates and Prices
Costa Rica and the Panama Canal 2017 (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Lindblad Deluxe Dates and Prices
Costa Rica and the Panama Canal 2017 (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Lindblad Deluxe Dates and Prices
Rainforest Cultures & Natural Ecosystems 9 Colon, Panama  Guayaquil, Ecuador  Expedition Silversea Deluxe Dates and Prices
Panama Unveiled 10 San Jose, Costa Rica  Panama City, Panama  Escorted Intrepid Budget Dates and Prices
Monteverde + Costa Rica & Panama 11 San Jose, Costa Rica  Panama City, Panama  Expedition Lindblad Deluxe Dates and Prices
Monteverde + Costa Rica & Panama 2017 11 San Jose, Costa Rica  Panama City, Panama  Expedition Lindblad Deluxe Dates and Prices
+ View all 21 multi-country vacations that include Panama
* Key to Quality Ratings

These vacations are classified according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered.

Budget = Budget vacations that typically range from $50 to $200 per person, per day, plus airfare.
First Class = First class vacations that typically range from $80 to $350 per person, per day, plus airfare.
Deluxe = Deluxe vacations that typically range from $200 to $650 per person, per day, plus airfare.
** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines.