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Panama Vacations

Panama, uniquely situated as a land bridge connecting North and South America, is famed for the Panama Canal that links the world's largest oceans. Many Panama tours visit the Miraflores Locks on the canal's Pacific entrance. Here, you can see millions of gallons of water transferred in mere minutes, all done by gravity.

Itineraries can also feature nocturnal wildlife cruises along the Chagres River and Gatun Lake, in search of howler monkeys, toucans and myriad reptiles; aerial tram tours through the forest canopy in Soberania National Park; and opportunities to meet the self-governing, indigenous Kuna people in the San Blas archipelago.

Book Now and Save on Panama Vacations!

  • Receive $400 to $800 per couple in air credit when you purchase select trips and flights through Globus. Book by September 30, 2014. Click here for eligible departures.
  • Save up to 10% on select Trafalgar vacations when you book and pay in full by November 20, 2014. Click here for eligible departures.
  • Save $1,000 per couple off select Alexander+Roberts itineraries when you pay in full at the time of booking. Click here for eligible departures.
  • Receive $400 to $800 per couple in air credit when you purchase select vacations and flights through Monograms. Book by September 30, 2014. Click here for eligible departures.
  • Save 15% to 20% off select G Adventures departures when you book by August 14, 2014. Click here for eligible departures.
  • Reduced rates with Ponant! Prices shown reflect discount. Click here for eligible departures.
  • Save $200 to $400 per couple off select Collette trips when you book by September 21, 2014. Click here for eligible departures.
  • Past Tauck guests receive a free pre- or post-tour one-night hotel stay on select 2015 departures when you book by September 26, 2014. Click here for eligible departures.
  • Group discounts! Book a group of 5-9 on the same Trafalgar tour and each person saves 5% off the land price. Book a group of 16 or more and one person travels for free. Click here for eligible departures.
  • Receive a free Be My Guest dining experience at an exclusive venue on select Trafalgar vacations. Click here for eligible departures.

The vacations below are divided into two groups. First, there is a list of trips that visit only Panama, followed by a list of multi-country itineraries that include Panama.

Trips are rated according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered. The vacations below are categorized according to the industry rating scale (budget, first class and deluxe). Click any vacation name for the itinerary, dates and prices.

Vacation Name Days Starts In Ends In Travel Style Company Quality*  
Vacations in Panama Only

Highlights of Panama 4 Panama City, Panama  Panama City, Panama  Independent SITA First Class Dates and Prices
5 Day Panama (Friday Departure) 5 Panama City, Panama  Panama City, Panama  Escorted Gate 1 First Class Dates and Prices
5 Day Panama (Wednesday Departure) 5 Panama City, Panama  Panama City, Panama  Escorted Gate 1 First Class Dates and Prices
Best of Panama 6 Panama City, Panama  Panama City, Panama  Independent Globus First Class Dates and Prices
Best of Panama 6 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Best of Panama 2015 6 Panama City, Panama  Panama City, Panama  Independent Globus First Class Dates and Prices
Best of Panama 2015 6 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Best of Panama 2014-2015 8 Panama City, Panama  Panama City, Panama  Escorted G Adventure Budget Dates and Prices
Panama, The Canal & Beyond 8 Panama City, Panama  Panama City, Panama  Escorted Brendan First Class Dates and Prices
Panama: The Canal and Beyond 8 Panama City, Panama  Panama City, Panama  Escorted Trafalgar First Class Dates and Prices
+ View all 42 vacations in Panama only
Multi-Country Vacations that Include Panama
Panama & Darien Park 2015 (Puerto Caldera - Willemstad ) 8 Puerto Caldera, Costa Rica  Williemstad, Curacao  Expedition Ponant Deluxe Dates and Prices
Costa Rica & the Panama Canal 2015 (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Lindblad Deluxe Dates and Prices
Costa Rica & the Panama Canal 2015 (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Lindblad Deluxe Dates and Prices
The Panama Canal & The Wonders of Costa Rica 2014-2015 (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Nat Hab Deluxe Dates and Prices
The Panama Canal & The Wonders of Costa Rica 2014-2015 (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Nat Hab Deluxe Dates and Prices
Rainforest Cultures & Natural Ecosystems 9 Colon, Panama  Guayaquil, Ecuador  Expedition Silversea Deluxe Dates and Prices
Panama Unveiled 2014-2015 10 San Jose, Costa Rica  Panama City, Panama  Escorted Intrepid Budget Dates and Prices
Panama the Canal and Beyond with Colonial Cartagena 2015 11 Panama City, Panama  Cartagena, Colombia  Escorted Trafalgar First Class Dates and Prices
Panama: The Canal and Beyond with Colonial Cartagena 11 Panama City, Panama  Cartagena, Colombia  Escorted Trafalgar First Class Dates and Prices
The Panama Canal & Costa Rica 2015 (Eastbound) 11 San Jose, Costa Rica  Panama City, Panama  Expedition Tauck Deluxe Dates and Prices
+ View all 21 multi-country vacations that include Panama
* Key to Quality Ratings

These vacations are classified according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered.

Budget = Budget vacations that typically range from $50 to $200 per person, per day, plus airfare.
First Class = First class vacations that typically range from $80 to $350 per person, per day, plus airfare.
Deluxe = Deluxe vacations that typically range from $200 to $650 per person, per day, plus airfare.
** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines.