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Panama Vacations

Panama, uniquely situated as a land bridge connecting North and South America, is famed for the Panama Canal that links the world's largest oceans. Many Panama tours visit the Miraflores Locks on the canal's Pacific entrance. Here, you can see millions of gallons of water transferred in mere minutes, all done by gravity.

Itineraries can also feature nocturnal wildlife cruises along the Chagres River and Gatun Lake, in search of howler monkeys, toucans and myriad reptiles; aerial tram tours through the forest canopy in Soberania National Park; and opportunities to meet the self-governing, indigenous Kuna people in the San Blas archipelago.

Book Now and Save on Panama Vacations!

  • Save with early payment discounts on select Trafalgar vacations when you book and pay in full. Prices shown reflect discounts of up to 7.5%. Expires February 28. Click here for eligible departures.
  • Save up to 25% off with early booking discounts on select 2017 and 2018 Hurtigruten voyages. Click here for eligible departures.
  • Save $600 per couple off select Alexander+Roberts itineraries when you pay in full at the time of booking. Click here for eligible departures.
  • Single travelers save $300 per person off select Alexander+Roberts trips when you book and pay in full. Click here for eligible departures.
  • Reduced rates with Ponant! Prices shown reflect discount. Click here for eligible departures.
  • Trafalgar Frequent Traveler Club members save up to 5% off the land price. Click here for eligible departures.
  • Monograms Journeys Club members save 5% off the cruise/land price. Click here for eligible departures.
  • Travel Loyalty by Collette members save an additional $100 to $150 per person off select Collette tours. Offer applies to guests who have traveled with Collette within the past two years and is combinable with other discounts. Click here for eligible departures.
  • Receive a free "Be My Guest" dining experience at an exclusive venue on select Trafalgar vacations. Click here for eligible departures.
  • Military members and their spouses save 5% off Scenic cruises. This offer does not apply to certain extensions. Click here for eligible departures.

The vacations below are divided into two groups. First, there is a list of trips that visit only Panama, followed by a list of multi-country itineraries that include Panama.

Trips are rated according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered. The vacations below are categorized according to the industry rating scale (budget, first class and deluxe). Click any vacation name for the itinerary, dates and prices.

Vacation Name Days Starts In Ends In Travel Style Company Quality*  
Vacations in Panama Only

Highlights of Panama 4 Panama City, Panama  Panama City, Panama  Independent SITA First Class Dates and Prices
5 Day Panama 5 Panama City, Panama  Panama City, Panama  Escorted Gate 1 First Class Dates and Prices
Best of Panama 6 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Best of Panama 8 Panama City, Panama  Panama City, Panama  Escorted G Adventure Budget Dates and Prices
8 Day Classic Panama 8 Panama City, Panama  Panama City, Panama  Escorted Gate 1 First Class Dates and Prices
Panama, the Canal and Beyond 8 Panama City, Panama  Panama City, Panama  Escorted Trafalgar First Class Dates and Prices
Panama, the Canal and Beyond Winter 8 Panama City, Panama  Panama City, Panama  Escorted Trafalgar First Class Dates and Prices
Best of Panama with San Blas Islands 9 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Best of Panama with Pacific Coast 9 Panama City, Panama  Panama City, Panama  Independent Monograms First Class Dates and Prices
Discover Panama 2017-2018 (Itinerary A) 9 Gamboa, Panama  Playa Bonita, Panama  Escorted Collette Deluxe Dates and Prices
+ View all 23 vacations in Panama only
Multi-Country Vacations that Include Panama
Colon - Fort de France 8 Colon, Panama  Fort de France, Martinique  Expedition Ponant Deluxe Dates and Prices
Costa Rica and the Panama Canal (Panama City to San Jose) 8 Panama City, Panama  San Jose, Costa Rica  Expedition Nat Hab Deluxe Dates and Prices
Costa Rica and the Panama Canal (San Jose to Panama City) 8 San Jose, Costa Rica  Panama City, Panama  Expedition Nat Hab Deluxe Dates and Prices
Panama, Colombia & Ecuador Discovery 8 Cartagena, Colombia  Guayaquil, Ecuador  Expedition Scenic Deluxe Dates and Prices
The Panama Canal & Costa Rica (BBC Earth Journey, Eastbound) 11 San Jose, Costa Rica  Panama City, Panama  Expedition Tauck Deluxe Dates and Prices
The Panama Canal & Costa Rica (BBC Earth Journey, Westbound) 11 Panama City, Panama  San Jose, Costa Rica  Expedition Tauck Deluxe Dates and Prices
The Panama Canal & Costa Rica 2018 (BBC Earth Journey, Eastbound) 11 San Jose, Costa Rica  Panama City, Panama  Expedition Tauck Deluxe Dates and Prices
The Panama Canal & Costa Rica 2018 (BBC Earth Journey, Westbound) 11 Panama City, Panama  San Jose, Costa Rica  Expedition Tauck Deluxe Dates and Prices
Costa Rica & Panama Discovery 13 San Jose, Costa Rica  Panama City, Panama  Escorted Intrepid Budget Dates and Prices
Panama Experience 14 San Jose, Costa Rica  Panama City, Panama  Escorted G Adventure Budget Dates and Prices
+ View all 16 multi-country vacations that include Panama
* Key to Quality Ratings

These vacations are classified according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered.

Budget = Budget vacations that typically range from $50 to $200 per person, per day, plus airfare.
First Class = First class vacations that typically range from $80 to $350 per person, per day, plus airfare.
Deluxe = Deluxe vacations that typically range from $200 to $650 per person, per day, plus airfare.
** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines.