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South America Vacations

Traveling to countries like Peru, Chile, Argentina and Brazil, our South America tours will introduce you to ancient civilizations, dazzling cities and time-honored crafts. See lush rain forests, fjords and towering waterfalls, or observe feathered macaws or penguin colonies. Many itineraries are designed as regional discoveries that visit the major cities in several countries, while others focus on one country in depth. Several of our trips utilize multiple modes of transportation, such as motorcoach travel or intra-tour flights. You also can hop from island to island in the Galapagos in a comfortable cruise ship or sail down the mighty Amazon River.

A tour director accompanies the group, speaking about the native cultures, traditions, history and sights along the way. Learn about the ancient Incas in Peru, where Machu Picchu -- the "Lost City of the Incas" -- is a prime attraction on tours. In Argentina, you might meet a gaucho, a South American cowboy and symbol of the country's national pride. If you schedule your trip accordingly, you can check out the festivities at Carnival in Rio de Janeiro, Brazil.

Learn how to dance the tango in Buenos Aires, sample the wines of Chile or watch the weavers of Taquile Island at work. Some itineraries offer adventurous options for the active traveler, like hiking or kayaking.

Book Now and Save on South America Vacations!

  • Save up to 15% off the land price of 2020 and 2021 Collette vacations when you also book your flights through Collette. Expires July 31. Click here for eligible departures.
  • Save 10% off 2021 Globus vacations. Click here for eligible departures.
  • Save 10% off 2021 Luxury Gold trips. Prices shown reflect discount. Click here for eligible departures.
  • Pay a reduced deposit of $99 per person on most CostSaver trips. Click here for eligible departures.
  • Save 10% on 2021 Insight trips. Prices shown reflect discount. Click here for eligible departures.
  • Save $100 per couple off 2021 Cosmos trips. Click here for eligible departures.
  • Save up to $1,100 per couple off Collette trips. Expires July 31. Click here for eligible departures.
  • Save $600 per couple off all Alexander+Roberts trips. Click here for eligible departures.
  • Save 15% off G Adventures trips. Price shown reflects discount. Expires July 31. Click here for eligible departures.
  • Travelers ages 18-35 save up to 20% off select Contiki trips. Prices shown reflect discount. Click here for eligible departures.

Trips are rated according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered. The vacations below are categorized according to the industry rating scale (budget, first class and deluxe). Click any vacation name for the itinerary, dates and prices.

Vacation Name Days Starts In Ends In Travel Style Company Quality*  
South America Vacations

Ushuaia to Ushuaia (16 Days) 16 Ushuaia, Argentina  Ushuaia, Argentina  Expedition Silversea Deluxe Dates and Prices
Coastal Adventure: Costa Rica to Peru 12 San Jose, Costa Rica  Lima, Peru  Expedition Scenic Deluxe Dates and Prices
Panama and Colombia Discovery 2021 10 Cartagena, Colombia  Lima, Peru  Expedition Scenic Deluxe Dates and Prices
Easter Island + Patagonia 11 Santiago, Chile  Santiago, Chile  Escorted A+R Deluxe Dates and Prices
Colon to Guayaquil 9 Colon, Panama  Guayaquil, Ecuador  Expedition Silversea Deluxe Dates and Prices
Taste of Argentina & Brazil with Grand Voyage of Discovery 2021 25 Buenos Aires, Argentina  Lisbon, Portugal  Expedition Scenic Deluxe Dates and Prices
Peruvian Amazon & Machu Picchu Exploration 15 Lima, Peru  Lima, Peru  River Cruise Uniworld Deluxe Dates and Prices
Lake Titicaca (Private Tour) 3 Puno, Peru  Puno, Peru  Independent A+R Deluxe Dates and Prices
Western Galapagos Cruise + Quito 10 Quito, Ecuador  Quito, Ecuador  Expedition A+R Deluxe Dates and Prices
Jewels of Latin America 13 Puerto Quetzal, Guatemala  Callao, Peru  Expedition Ponant Deluxe Dates and Prices
Machu Picchu + the Galapagos Cruise 2020-2021 14 Lima, Peru  Quito, Ecuador  Expedition A+R Deluxe Dates and Prices
Patagonia: Edge of the World featuring Argentina, Chile, and a 4-Night Patagonia Cruise 2020-2021 14 Buenos Aires, Argentina  Buenos Aires, Argentina  Escorted Collette Deluxe Dates and Prices
Ultimate America Discovery 2021 20 Boston, MA  Cartagena, Colombia  Expedition Scenic Deluxe Dates and Prices
Pure Patagonia (Private Tour) 9 Santiago, Chile  Santiago, Chile  Escorted A+R Deluxe Dates and Prices
Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise 2020-2021 15 Lima, Peru  Quito, Ecuador  Escorted Collette Deluxe Dates and Prices
The Caribbean & Amazon River 13 Cayenne, French Guiana  Fort de France, Martinique  Expedition Ponant Deluxe Dates and Prices
Antarctica in Depth with Patagonian Adventure 2020-2021 21 Buenos Aires, Argentina  Santiago, Chile  Expedition Scenic Deluxe Dates and Prices
Chilean Fjords & Cape Horn with Taste of Argentina & Brazil 20 Santiago, Chile  Rio de Janeiro, Brazil  Expedition Scenic Deluxe Dates and Prices
Peru and the Galapagos Islands 2021 (BBC Earth Journey) 15 Lima, Peru  Guayaquil, Ecuador  Expedition Tauck Deluxe Dates and Prices
Best of Chile from Atacama to Patagonia 2021 11 Santiago, Chile  Santiago, Chile  Escorted Insight Deluxe Dates and Prices
+ View all 1,082 South America vacations
* Key to Quality Ratings

These vacations are classified according to the quality of accommodations, the number of included amenities and activities, and the level of service delivered.

Budget = Budget vacations that typically range from $50 to $200 per person, per day, plus airfare.
First Class = First class vacations that typically range from $80 to $350 per person, per day, plus airfare.
Deluxe = Deluxe vacations that typically range from $200 to $650 per person, per day, plus airfare.
** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines.